Research Laboratory - Chitrangana Singha

Hello, I'm Chitrangana Singha

Biotech Researcher | Protein Biophysics | Human Anatomy Specialist

Exploring the frontiers of biotechnology with a focus on protein structures and innovative disease treatments. Currently pursuing post-graduate studies in Japan at the Laboratory of Protein Biophysics.

About Me

I am a passionate biotech researcher with a deep interest in human anatomy and developing innovative treatments for diseases. My research journey has led me to Japan, where I am currently pursuing post-graduate studies at the prestigious Laboratory of Protein Biophysics.

My work focuses on understanding protein structures and their role in disease mechanisms, with the goal of developing targeted therapies that can improve human health and longevity. I combine traditional biochemical approaches with cutting-edge computational methods to explore the complex world of cellular biology.

Beyond the laboratory, I maintain a balanced lifestyle through yoga, resistance training, and running. I'm an avid reader who enjoys exploring scientific literature as well as philosophy and fiction. This holistic approach to life informs my research, helping me see connections across disciplines and inspiring innovative solutions to complex problems.

Research Focus

  • Protein Structure Analysis
  • Neurodegenerative Diseases
  • Drug Target Identification

Technical Skills

  • X-ray Crystallography
  • Molecular Dynamics
  • CRISPR-Cas9 Gene Editing

Personal Interests

  • Yoga & Resistance Training
  • Muscle Hypertrophy Research
  • Scientific Literature

Research Publications

2023
Journal of Molecular Biology

Structural Insights into Protein-Protein Interactions in Cellular Signaling Pathways

This paper presents novel findings on the structural basis of key protein-protein interactions involved in cellular signaling, with implications for drug discovery and therapeutic intervention in various diseases.

2022
Nature Neuroscience

Novel Approaches to Targeting Protein Aggregation in Neurodegenerative Disorders

This review article discusses emerging strategies for preventing and reversing protein aggregation in conditions such as Alzheimer's and Parkinson's disease, highlighting recent advances in the field.

2021
Journal of Computational Chemistry

Computational Prediction of Protein-Ligand Binding Affinities: A Machine Learning Approach

This research paper presents a novel machine learning algorithm for predicting the binding affinities of small molecules to protein targets, with applications in virtual screening and drug discovery.

Blog

The Intersection of Exercise Science and Molecular Biology

This article explores the molecular mechanisms behind muscle hypertrophy and how understanding these pathways can inform both exercise regimens and therapeutic interventions for muscle-wasting conditions.

April 15, 2023

Mindfulness in Scientific Research: A Personal Journey

This reflective piece discusses how mindfulness practices like yoga can enhance scientific thinking, problem-solving, and creativity in the laboratory, drawing from personal experiences and scientific literature.

March 2, 2023

Navigating Academic Research in Japan

This article shares personal experiences and practical advice for researchers considering international academic opportunities, with a focus on adapting to Japanese research culture and environment.

February 18, 2023

The Future of Personalized Medicine

This forward-looking article examines how advances in biotechnology, genomics, and computational biology are paving the way for truly personalized medical treatments tailored to individual genetic profiles.

January 5, 2023

Research Projects

Protein Misfolding Project
Ongoing

Protein Misfolding in Neurodegenerative Diseases

This project explores the molecular mechanisms behind protein misfolding and aggregation in neurodegenerative disorders, with a focus on developing novel therapeutic approaches to prevent or reverse these processes.

Alzheimer'sProtein AggregationDrug Discovery
Drug Delivery Project
Collaboration

Targeted Drug Delivery Systems

This research focuses on designing smart drug delivery systems that can specifically target cancer cells while minimizing side effects on healthy tissues, improving the efficacy and safety of cancer treatments.

NanoparticlesCancer TherapyTargeted Delivery
CRISPR Project
New

CRISPR-Based Therapeutic Approaches

This research explores the application of CRISPR-Cas9 technology for correcting genetic mutations associated with inherited diseases, with a focus on delivery methods and minimizing off-target effects.

CRISPRGene TherapyGenetic Disorders

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